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Chemical Inhibition of Bacterial Ribosome Biogenesis Shows Efficacy in a Worm Infection Model

The development of antibacterial compounds that perturb novel processes is an imperative in the challenge presented by widespread antibiotic resistance. While many antibiotics target the ribosome, molecules that inhibit ribosome assembly have yet to be used in this manner. Here we show that a novel...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Stokes, Jonathan M., Selin, Carrie, Cardona, Silvia T., Brown, Eric D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394774/
https://ncbi.nlm.nih.gov/pubmed/25712357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04690-14
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