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A high-throughput screen of the GTPase activity of Escherichia coli EngA to find an inhibitor of bacterial ribosome biogenesis

The synthesis of ribosomes is an essential process, which is aided by a variety of transacting factors in bacteria. Among these is a group of GTPases essential for bacterial viability and emerging as promising targets for new antibacterial agents. Herein, we describe a robust high-throughput screeni...

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Detalhes bibliográficos
Main Authors: Bharat, Amrita, Blanchard, Jan E., Brown, Eric D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061131/
https://ncbi.nlm.nih.gov/pubmed/23606650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113486001
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