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Activated PI3K Signaling as an Endogenous Inducer of p53 in Human Cancer

Complex pathways exist in mammalian cells to regulate the expression and activity of oncogenes and tumor suppressor genes. Defining these regulatory pathways is an important step towards being able to interfere with tumorigenesis. Here we discuss our recent study indicating that activation of the ph...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Lee, Carolyn, Kim, Jung-Sik, Waldman, Todd
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394610/
https://ncbi.nlm.nih.gov/pubmed/17329971
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