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p53 and PI3K/AKT Signalings Are Up-Regulated in Flies with Defects in the THO Complex

The THO complex (THO) is an evolutionary conserved protein required for the formation of export-competent mRNP. The growing evidence indicates that the metazoan THO plays important roles in cell differentiation and cellular stress response. But the underlying mechanisms are poorly understood. Herein...

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Bibliografiske detaljer
Main Authors: Moon, Sungjin, Chung, Yun Doo
Format: Artigo
Sprog:Inglês
Udgivet: Korea Society for Molecular and Cellular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887910/
https://ncbi.nlm.nih.gov/pubmed/23475424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-0009-x
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