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Mitochondrial anti-oxidant protects IEX-1 deficient mice from organ damage during endotoxemia

Sepsis, a leading cause of mortality in intensive care units worldwide, is often a result of overactive and systemic inflammation following serious infections. We found that mice lacking immediate early responsive gene X-1 (IEX-1) were prone to lipopolysaccharide (LPS) -induced endotoxemia. A nonlet...

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Bibliografiska uppgifter
I publikationen:Int Immunopharmacol
Huvudupphovsmän: Ramsey, Haley, Wu, Mei X.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394602/
https://ncbi.nlm.nih.gov/pubmed/25466275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2014.10.019
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