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Reduced oxidative tissue damage during endotoxemia in IRAK-1 deficient mice
The generation of reactive oxygen species (ROS) triggered by bacterial endotoxin lipopolysaccharide (LPS) plays a key role during the pathogenesis of sepsis. Given the key role that the interleukin-1 receptor associated kinase-1 (IRAK-1) plays in LPS-mediated Toll-like-receptor 4 (TLR4) pathway, we...
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| 出版年: | Mol Immunol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440666/ https://ncbi.nlm.nih.gov/pubmed/22364946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.01.011 |
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