IEX-1 deficiency induces browning of white adipose tissue and resists diet-induced obesity

Chronic inflammation plays a crucial role in the pathogenesis of obesity and insulin resistance. However, the primary mediators that affect energy homeostasis remain ill defined. Here, we report an unexpected role for immediate early response gene X-1 (IEX-1), a downstream target of NF-κB, in energy...

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Udgivet i:Sci Rep
Main Authors: Shahid, Mohd, Javed, Ammar A., Chandra, David, Ramsey, Haley E., Shah, Dilip, Khan, Mohammed F., Zhao, Liping, Wu, Mei X.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827096/
https://ncbi.nlm.nih.gov/pubmed/27063893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24135
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