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Phosphorylation of ORF1p is required for L1 retrotransposition
Although members of the L1 (LINE-1) clade of non-LTR retrotransposons can be deleterious, the L1 clade has remained active in most mammals for ∼100 million years and generated almost 40% of the human genome. The details of L1–host interaction are largely unknown, however. Here we report that L1 acti...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394301/ https://ncbi.nlm.nih.gov/pubmed/25831499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416869112 |
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