Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases

AIM: To investigate whether whole-exome sequencing may serve as an efficient method to identify known or novel colorectal cancer (CRC) predisposing genes in early-onset or familial CRC cases. METHODS: We performed whole-exome sequencing in 23 Chinese patients from 21 families with non-polyposis CRC...

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Dettagli Bibliografici
Pubblicato in:World J Gastroenterol
Autori principali: Zhang, Jun-Xiao, Fu, Lei, de Voer, Richarda M, Hahn, Marc-Manuel, Jin, Peng, Lv, Chen-Xi, Verwiel, Eugène TP, Ligtenberg, Marjolijn JL, Hoogerbrugge, Nicoline, Kuiper, Roland P, Sheng, Jian-Qiu, Geurts van Kessel, Ad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Inc 2015
Soggetti:
Basic Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394074/
https://ncbi.nlm.nih.gov/pubmed/25892863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i14.4136
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