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Observing a Lipid-Dependent Alteration in Single Lactose Permeases

Lipids of the Escherichia coli membrane are mainly composed of 70–80% phosphatidylethanolamine (PE) and 20–25% phosphatidylglycerol (PG). Biochemical studies indicate that the depletion of PE causes inversion of the N-terminal helix bundle of the lactose permease (LacY), and helix VII becomes extram...

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發表在:Structure
Main Authors: Serdiuk, Tetiana, Sugihara, Junichi, Mari, Stefania A., Kaback, H. Ronald, Müller, Daniel J.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394043/
https://ncbi.nlm.nih.gov/pubmed/25800555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.02.009
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