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Overcoming T cell exhaustion in infection and cancer
Inhibitors of the PD-1:PD-L1 pathway, a central regulator of T cell exhaustion, have been recently shown to be effective for treatment of different cancers. However, clinical responses are mixed, highlighting the need to better understand the mechanisms of action of PD-1:PD-L1, the role of this path...
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| Publicado en: | Trends Immunol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4393798/ https://ncbi.nlm.nih.gov/pubmed/25797516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2015.02.008 |
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