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The Impact of Covariate Adjustment at Randomization and Analysis For Binary Outcomes: Understanding Differences Between Superiority and Non-Inferiority Trials
The question of when to adjust for important prognostic covariates often arises in the design of clinical trials, and there remain various opinions on whether to adjust during both randomization and analysis, at randomization alone, or at analysis alone. Furthermore, little is known about the impact...
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Publicado no: | Stat Med |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4393769/ https://ncbi.nlm.nih.gov/pubmed/25641057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6447 |
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