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Prevention of autoimmune lysis by T cells with specificity for a heat shock protein by antisense oligonucleotide treatment.

T lymphocytes with specificity for the bacterial heat shock protein (hsp) 60 recognize stressed host cells, thus possibly promoting pathogenesis of certain infectious and autoimmune diseases. Here, we show that autoimmune destruction of stressed Schwann cells and macrophages by cytotoxic T lymphocyt...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Steinhoff, U, Zügel, U, Wand-Württenberger, A, Hengel, H, Rösch, R, Munk, M E, Kaufmann, S H
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43936/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7910966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.5085
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