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Prevention of autoimmune lysis by T cells with specificity for a heat shock protein by antisense oligonucleotide treatment.

T lymphocytes with specificity for the bacterial heat shock protein (hsp) 60 recognize stressed host cells, thus possibly promoting pathogenesis of certain infectious and autoimmune diseases. Here, we show that autoimmune destruction of stressed Schwann cells and macrophages by cytotoxic T lymphocyt...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Steinhoff, U, Zügel, U, Wand-Württenberger, A, Hengel, H, Rösch, R, Munk, M E, Kaufmann, S H
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1994
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43936/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7910966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.5085
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