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Prevention of autoimmune lysis by T cells with specificity for a heat shock protein by antisense oligonucleotide treatment.

T lymphocytes with specificity for the bacterial heat shock protein (hsp) 60 recognize stressed host cells, thus possibly promoting pathogenesis of certain infectious and autoimmune diseases. Here, we show that autoimmune destruction of stressed Schwann cells and macrophages by cytotoxic T lymphocyt...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Steinhoff, U, Zügel, U, Wand-Württenberger, A, Hengel, H, Rösch, R, Munk, M E, Kaufmann, S H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43936/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7910966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.5085
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