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Adeno-associated virus type 2 vectors: transduction and long-term expression in cerebellar Purkinje cells in vivo is mediated by the fibroblast growth factor receptor 1: bFGFR-1 mediates AAV2 transduction of Purkinje cells

The receptor for adeno-associated virus sero-type 2 (AAV2) in Purkinje cells has not been identified, but based on work carried out in non-neuronal cell lines, heparan sulfate proteoglycan is thought to act as a primary receptor, with basic fibroblast growth factor receptor-1 being reported as a co-...

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Detalhes bibliográficos
Publicado no:Arch Virol
Main Authors: Belur, Lalitha R., Kaemmerer, William F., McIvor, R. Scott, Low, Walter C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393077/
https://ncbi.nlm.nih.gov/pubmed/18937030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-008-0222-7
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