Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice

A major etiological risk factor for hepatocellular carcinoma (HCC) is infection by Hepatitis viruses, especially hepatitis B virus and hepatitis C virus. Hepatitis B virus and hepatitis C virus do not cause aggressive activation of an oncogenic pathway, but they transactivate a broad array of genes,...

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Bibliographische Detailangaben
Veröffentlicht in:Carcinogenesis
Hauptverfasser: Yamada, Hiroshi Y., Zhang, Yuting, Reddy, Arun, Mohammed, Altaf, Lightfoot, Stan, Dai, Wei, Rao, Chinthalapally V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Original Manuscript
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392605/
https://ncbi.nlm.nih.gov/pubmed/25740822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv011
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