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Myeloperoxidase-dependent Lipid Peroxidation Promotes the Oxidative Modification of Cytosolic Proteins in Phagocytic Neutrophils

Phagocytic neutrophils generate reactive oxygen species to kill microbes. Oxidant generation occurs within an intracellular phagosome, but diffusible species can react with the neutrophil and surrounding tissue. To investigate the extent of oxidative modification, we assessed the carbonylation of cy...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Wilkie-Grantham, Rachel P., Magon, Nicholas J., Harwood, D. Tim, Kettle, Anthony J., Vissers, Margreet C., Winterbourn, Christine C., Hampton, Mark B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392286/
https://ncbi.nlm.nih.gov/pubmed/25697357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.613422
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