Myeloperoxidase-dependent Lipid Peroxidation Promotes the Oxidative Modification of Cytosolic Proteins in Phagocytic Neutrophils

Phagocytic neutrophils generate reactive oxygen species to kill microbes. Oxidant generation occurs within an intracellular phagosome, but diffusible species can react with the neutrophil and surrounding tissue. To investigate the extent of oxidative modification, we assessed the carbonylation of cy...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Wilkie-Grantham, Rachel P., Magon, Nicholas J., Harwood, D. Tim, Kettle, Anthony J., Vissers, Margreet C., Winterbourn, Christine C., Hampton, Mark B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Metabolism
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392286/
https://ncbi.nlm.nih.gov/pubmed/25697357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.613422
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