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Rescue of Na(+) Affinity in Aspartate 928 Mutants of Na(+),K(+)-ATPase by Secondary Mutation of Glutamate 314
The Na(+),K(+)-ATPase binds Na(+) at three transport sites denoted I, II, and III, of which site III is Na(+)-specific and suggested to be the first occupied in the cooperative binding process activating phosphorylation from ATP. Here we demonstrate that the asparagine substitution of the aspartate...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392278/ https://ncbi.nlm.nih.gov/pubmed/25713066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.625509 |
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