載入...

Activated α(2)-Macroglobulin Binding to Human Prostate Cancer Cells Triggers Insulin-like Responses

Ligation of cell surface GRP78 by activated α(2)-macroglobulin (α(2)M*) promotes cell proliferation and suppresses apoptosis. α(2)M*-treated human prostate cancer cells exhibit a 2–3-fold increase in glucose uptake and lactate secretion, an effect similar to insulin treatment. In both α(2)M* and ins...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Biol Chem
Main Authors: Misra, Uma Kant, Pizzo, Salvatore Vincent
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392261/
https://ncbi.nlm.nih.gov/pubmed/25720493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.617837
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!