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Extracellular Processing of the Cartilage Proteoglycan Aggregate and Its Effect on CD44-mediated Internalization of Hyaluronan

In many cells hyaluronan receptor CD44 mediates the endocytosis of hyaluronan and its delivery to endosomes/lysosomes. The regulation of this process remains largely unknown. In most extracellular matrices hyaluronan is not present as a free polysaccharide but often is found in complex with other sm...

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Pubblicato in:J Biol Chem
Autori principali: Danielson, Ben T., Knudson, Cheryl B., Knudson, Warren
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392260/
https://ncbi.nlm.nih.gov/pubmed/25733665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.643171
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