Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome

BACKGROUND: DNA hypermethylation is reported as a frequent event and prognostic marker in head and neck squamous cell carcinomas (HNSCC). Methylation has been commonly assessed with non-quantitative methodologies, such as methylation-specific PCR (MSP). We investigated previously reported hypermethy...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Lim, Annette M, Candiloro, Ida LM, Wong, Nicholas, Collins, Marnie, Do, Hongdo, Takano, Elena A, Angel, Christopher, Young, Richard J, Corry, June, Wiesenfeld, David, Kleid, Stephen, Sigston, Elizabeth, Lyons, Bernard, Rischin, Danny, Solomon, Benjamin, Dobrovic, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391486/
https://ncbi.nlm.nih.gov/pubmed/25859283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-6-22
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