Frequency and prognostic significance of p16(INK4A) protein overexpression and transcriptionally active human papillomavirus infection in laryngeal squamous cell carcinoma

BACKGROUND: Human papillomavirus (HPV) infection is a powerful prognostic biomarker in a subset of head and neck squamous cell carcinomas, specifically oropharyngeal cancers. However, the role of HPV in non-oropharyngeal sites, such as the larynx, remains unconfirmed. METHODS: We evaluated a cohort...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Young, R J, Urban, D, Angel, C, Corry, J, Lyons, B, Vallance, N, Kleid, S, Iseli, T A, Solomon, B, Rischin, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366899/
https://ncbi.nlm.nih.gov/pubmed/25688737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.59
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