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Preclinical Evaluation of a Novel SIRT1 Modulator SRT1720 in Multiple Myeloma Cells
SIRT1 belongs to the silent information regulator 2 (Sir2) protein family of enzymes and functions as a NAD(+)-dependent class III histone deacetylase. Here, we examined the anti-multiple myeloma (MM) activity of a novel oral agent, SRT1720, which targets SIRT1. Treatment of MM cells with SRT1720 in...
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| Publicado no: | Br J Haematol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4391196/ https://ncbi.nlm.nih.gov/pubmed/21950728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08888.x |
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