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A novel vascular disrupting agent plinabulin triggers JNK-mediated apoptosis and inhibits angiogenesis in multiple myeloma cells

Previous studies have established a role of vascular-disrupting agents as anti- cancer agents. Plinabulin is a novel vascular-disrupting agent that exhibits potent interruption of tumor blood flow because of the disruption of tumor vascular endothelial cells, resulting in tumor necrosis. In addition...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Singh, Ajita V., Bandi, Madhavi, Raje, Noopur, Richardson, Paul, Palladino, Michael A., Chauhan, Dharminder, Anderson, Kenneth C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110026/
https://ncbi.nlm.nih.gov/pubmed/21454451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-323857
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