Combined QTL and Selective Sweep Mappings with Coding SNP Annotation and cis-eQTL Analysis Revealed PARK2 and JAG2 as New Candidate Genes for Adiposity Regulation

Very few causal genes have been identified by quantitative trait loci (QTL) mapping because of the large size of QTL, and most of them were identified thanks to functional links already known with the targeted phenotype. Here, we propose to combine selection signature detection, coding SNP annotatio...

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Publicado no:G3 (Bethesda)
Main Authors: Roux, Pierre-François, Boitard, Simon, Blum, Yuna, Parks, Brian, Montagner, Alexandra, Mouisel, Etienne, Djari, Anis, Esquerré, Diane, Désert, Colette, Boutin, Morgane, Leroux, Sophie, Lecerf, Frédéric, Le Bihan-Duval, Elisabeth, Klopp, Christophe, Servin, Bertrand, Pitel, Frédérique, Duclos, Michel Jean, Guillou, Hervé, Lusis, Aldons J., Demeure, Olivier, Lagarrigue, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
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Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390568/
https://ncbi.nlm.nih.gov/pubmed/25653314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.016865
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