Combined QTL and Selective Sweep Mappings with Coding SNP Annotation and cis-eQTL Analysis Revealed PARK2 and JAG2 as New Candidate Genes for Adiposity Regulation

Very few causal genes have been identified by quantitative trait loci (QTL) mapping because of the large size of QTL, and most of them were identified thanks to functional links already known with the targeted phenotype. Here, we propose to combine selection signature detection, coding SNP annotatio...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:G3 (Bethesda)
Main Authors: Roux, Pierre-François, Boitard, Simon, Blum, Yuna, Parks, Brian, Montagner, Alexandra, Mouisel, Etienne, Djari, Anis, Esquerré, Diane, Désert, Colette, Boutin, Morgane, Leroux, Sophie, Lecerf, Frédéric, Le Bihan-Duval, Elisabeth, Klopp, Christophe, Servin, Bertrand, Pitel, Frédérique, Duclos, Michel Jean, Guillou, Hervé, Lusis, Aldons J., Demeure, Olivier, Lagarrigue, Sandrine
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2015
Teme:
Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390568/
https://ncbi.nlm.nih.gov/pubmed/25653314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.016865
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