Combined QTL and Selective Sweep Mappings with Coding SNP Annotation and cis-eQTL Analysis Revealed PARK2 and JAG2 as New Candidate Genes for Adiposity Regulation

Very few causal genes have been identified by quantitative trait loci (QTL) mapping because of the large size of QTL, and most of them were identified thanks to functional links already known with the targeted phenotype. Here, we propose to combine selection signature detection, coding SNP annotatio...

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Opis bibliograficzny
Wydane w:G3 (Bethesda)
Główni autorzy: Roux, Pierre-François, Boitard, Simon, Blum, Yuna, Parks, Brian, Montagner, Alexandra, Mouisel, Etienne, Djari, Anis, Esquerré, Diane, Désert, Colette, Boutin, Morgane, Leroux, Sophie, Lecerf, Frédéric, Le Bihan-Duval, Elisabeth, Klopp, Christophe, Servin, Bertrand, Pitel, Frédérique, Duclos, Michel Jean, Guillou, Hervé, Lusis, Aldons J., Demeure, Olivier, Lagarrigue, Sandrine
Format: Artigo
Język:Inglês
Wydane: Genetics Society of America 2015
Hasła przedmiotowe:
Investigations
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390568/
https://ncbi.nlm.nih.gov/pubmed/25653314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.016865
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