Combined QTL and Selective Sweep Mappings with Coding SNP Annotation and cis-eQTL Analysis Revealed PARK2 and JAG2 as New Candidate Genes for Adiposity Regulation

Very few causal genes have been identified by quantitative trait loci (QTL) mapping because of the large size of QTL, and most of them were identified thanks to functional links already known with the targeted phenotype. Here, we propose to combine selection signature detection, coding SNP annotatio...

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Detalles Bibliográficos
Publicado en:G3 (Bethesda)
Autores principales: Roux, Pierre-François, Boitard, Simon, Blum, Yuna, Parks, Brian, Montagner, Alexandra, Mouisel, Etienne, Djari, Anis, Esquerré, Diane, Désert, Colette, Boutin, Morgane, Leroux, Sophie, Lecerf, Frédéric, Le Bihan-Duval, Elisabeth, Klopp, Christophe, Servin, Bertrand, Pitel, Frédérique, Duclos, Michel Jean, Guillou, Hervé, Lusis, Aldons J., Demeure, Olivier, Lagarrigue, Sandrine
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2015
Materias:
Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390568/
https://ncbi.nlm.nih.gov/pubmed/25653314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.016865
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