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Targeting the Small- and Intermediate-Conductance Ca(2+)-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface
The small- and intermediate-conductance Ca(2+)-activated potassium (SK/IK) channels play important roles in the regulation of excitable cells in both the central nervous and cardiovascular systems. Evidence from animal models has implicated SK/IK channels in neurological conditions such as ataxia an...
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| Publicado no: | Neurosignals |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390548/ https://ncbi.nlm.nih.gov/pubmed/25300231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000367896 |
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