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Targeting the Small- and Intermediate-Conductance Ca(2+)-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface

The small- and intermediate-conductance Ca(2+)-activated potassium (SK/IK) channels play important roles in the regulation of excitable cells in both the central nervous and cardiovascular systems. Evidence from animal models has implicated SK/IK channels in neurological conditions such as ataxia an...

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Dettagli Bibliografici
Pubblicato in:Neurosignals
Autori principali: Cui, Meng, Qin, Guangrong, Yu, Kunqian, Bowers, M. Scott, Zhang, Miao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390548/
https://ncbi.nlm.nih.gov/pubmed/25300231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000367896
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