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Genetically modified bacteria as a tool to detect microscopic solid tumor masses with triggered release of a recombinant biomarker

Current tomographic methods of cancer detection have limited sensitivity and are unable to detect malignant masses smaller than half a centimeter in diameter. Mortality from tumor recurrence and metastatic disease would be reduced if small lesions could be detected earlier. To overcome this limitati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Integr Biol (Camb)
Hauptverfasser: Panteli, Jan T., Forkus, Brittany A., Van Dessel, Nele, Forbes, Neil S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390529/
https://ncbi.nlm.nih.gov/pubmed/25737274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ib00047e
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