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Engineered bacteria detect spatial profiles in glucose concentration within solid tumor cell masses

Tumor heterogeneity makes cancer difficult to treat. Many small molecule cancer drugs target rapidly dividing cells on the periphery of tumors but have difficulty in penetrating deep into tumors and are ineffective at treating entire tumors. Targeting both rapidly dividing and slower growing regions...

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Bibliografiska uppgifter
I publikationen:Biotechnol Bioeng
Huvudupphovsmän: Panteli, Jan T., Forbes, Neil S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037000/
https://ncbi.nlm.nih.gov/pubmed/27159665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26006
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