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In Vitro Metabolism and Stability of the Actinide Chelating Agent 3,4,3-LI(1,2-HOPO)

The hydroxypyridinonate ligand 3,4,3-LI(1,2-HOPO) is currently under development for radionuclide chelation therapy. The preclinical characterization of this highly promising ligand comprised the evaluation of its in vitro properties, including microsomal, plasma, and gastrointestinal fluid stabilit...

詳細記述

保存先:
書誌詳細
出版年:J Pharm Sci
主要な著者: Choi, Taylor A., Furimsky, Anna M., Swezey, Robert, Bunin, Deborah I., Byrge, Patricia, Iyer, Lalitha V., Chang, Polly Y., Abergel, Rebecca J.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390475/
https://ncbi.nlm.nih.gov/pubmed/25727482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24394
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