In Vitro Metabolism and Stability of the Actinide Chelating Agent 3,4,3-LI(1,2-HOPO)

The hydroxypyridinonate ligand 3,4,3-LI(1,2-HOPO) is currently under development for radionuclide chelation therapy. The preclinical characterization of this highly promising ligand comprised the evaluation of its in vitro properties, including microsomal, plasma, and gastrointestinal fluid stabilit...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Choi, Taylor A., Furimsky, Anna M., Swezey, Robert, Bunin, Deborah I., Byrge, Patricia, Iyer, Lalitha V., Chang, Polly Y., Abergel, Rebecca J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390475/
https://ncbi.nlm.nih.gov/pubmed/25727482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24394
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