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Novel Protein kinase C θ: Coronin 1A complex in T lymphocytes

BACKGROUND: Protein kinase C-θ (PKCθ) plays an important role in signal transduction down-stream of the T cell receptor and T cells deficient of PKCθ show impaired NF-κB as well as NFAT/AP-1 activation resulting in strongly decreased IL-2 expression and proliferation. However, it is not yet entirely...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Siegmund, Kerstin, Thuille, Nikolaus, Posch, Nina, Fresser, Friedrich, Baier, Gottfried
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390099/
https://ncbi.nlm.nih.gov/pubmed/25889880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0100-3
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