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Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCθ in T lymphocytes
Phosphopeptide mapping identified a major autophosphorylation site, phospho (p)Thr-219, between the tandem C1 domains of the regulatory fragment in protein kinase C (PKC)θ. Confirmation of this identification was derived using (p)Thr-219 antisera that reacted with endogenous PKCθ in primary CD3(+) T...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2005
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283955/ https://ncbi.nlm.nih.gov/pubmed/16252004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600856 |
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