HMGB1 is involved in autophagy inhibition caused by SNCA/α-synuclein overexpression: A process modulated by the natural autophagy inducer corynoxine B

SNCA/α-synuclein and its rare mutations are considered as the culprit proteins in Parkinson disease (PD). Wild-type (WT) SNCA has been shown to impair macroautophagy in mammalian cells and in transgenic mice. In this study, we monitored the dynamic changes in autophagy process and confirmed that ove...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Song, Ju-Xian, Lu, Jia-Hong, Liu, Liang-Feng, Chen, Lei-Lei, Durairajan, Siva Sundara Kumar, Yue, Zhenyu, Zhang, Hong-Qi, Li, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Translational Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389868/
https://ncbi.nlm.nih.gov/pubmed/24178442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.26751
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados