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NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models
Alzheimer disease (AD) is the most common neurodegenerative disease characterized by the deposition of amyloid plaque in the brain. The autophagy-associated PIK3C3-containing phosphatidylinositol 3-kinase (PtdIns3K) complex has been shown to interfere with APP metabolism and amyloid beta peptide (Aβ...
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| Publicado no: | Autophagy |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5788544/ https://ncbi.nlm.nih.gov/pubmed/28980867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1379633 |
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