Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase
The insulin-like growth factor I/insulin receptor substrate 1 axis controls, in a nonredundant way, ≈50% of cell and body size in animals from Drosophila to mice and in cells in culture. Although other factors may also intervene, cell size is strongly dependent on ribosome biogenesis, which is under...
Збережено в:
| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
2004
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC438966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15197263/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403328101 |
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