Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase
The insulin-like growth factor I/insulin receptor substrate 1 axis controls, in a nonredundant way, ≈50% of cell and body size in animals from Drosophila to mice and in cells in culture. Although other factors may also intervene, cell size is strongly dependent on ribosome biogenesis, which is under...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC438966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15197263/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403328101 |
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