Chargement en cours...
The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and β(2)-microglobulin-deficient hepatocytes
The antimicrobial peptide hepcidin appears to play a central role in the regulation of iron homeostasis. In intact animals, iron overload or the injection of lipopolysaccharide (LPS) stimulates transcription of HAMP, the gene that encodes hepcidin. In isolated hepatocytes, IL-6, an inflammatory cyto...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2004
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC438964/ https://ncbi.nlm.nih.gov/pubmed/15192150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403108101 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|