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Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6

Recently, it has been suggested that hepcidin, a peptide involved in iron homeostasis, is regulated by bone morphogenetic proteins (BMPs), apparently by binding to hemojuvelin (Hjv) as a coreceptor and signaling through Smad4. We investigate the role of Hfe, Tfr2 (transferrin receptor 2), and IL-6 i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Truksa, Jaroslav, Peng, Hongfan, Lee, Pauline, Beutler, Ernest
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502450/
https://ncbi.nlm.nih.gov/pubmed/16801541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603124103
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