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Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate
The widespread emergence of Plasmodium falciparum (Pf) strains resistant to frontline agents has fuelled the search for fast-acting agents with novel mechanism of action. Here, we report the discovery and optimization of novel antimalarial compounds, the triaminopyrimidines (TAPs), which emerged fro...
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Gepubliceerd in: | Nat Commun |
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Hoofdauteurs: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Nature Pub. Group
2015
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4389225/ https://ncbi.nlm.nih.gov/pubmed/25823686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7715 |
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