In Silico-Based High-Throughput Screen for Discovery of Novel Combinations for Tuberculosis Treatment

There are currently 18 drug classes for the treatment of tuberculosis, including those in the development pipeline. An in silico simulation enabled combing the innumerably large search space to derive multidrug combinations. Through the use of ordinary differential equations (ODE), we constructed an...

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Opis bibliograficzny
Wydane w:Antimicrob Agents Chemother
Główni autorzy: Singh, Ragini, Ramachandran, Vasanthi, Shandil, Radha, Sharma, Sreevalli, Khandelwal, Swati, Karmarkar, Malancha, Kumar, Naveen, Solapure, Suresh, Saralaya, Ramanatha, Nanduri, Robert, Panduga, Vijender, Reddy, Jitendar, Prabhakar, K. R., Rajagopalan, Swaminathan, Rao, Narasimha, Narayanan, Shridhar, Anandkumar, Anand, Balasubramanian, V., Datta, Santanu
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology 2015
Hasła przedmiotowe:
Experimental Therapeutics
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538536/
https://ncbi.nlm.nih.gov/pubmed/26149995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05148-14
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