Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells

Predisposition to sporadic Alzheimer’s disease (SAD) involves interactions between a person’s unique combination of genetic variants and the environment. The molecular effect of these variants may be subtle and difficult to analyze with standard in vitro or in vivo models. Here we used hIPSCs to exa...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Stem Cell
Autori principali: Young, Jessica E., Boulanger-Weill, Jonathan, Williams, Daniel A., Woodruff, Grace, Buen, Floyd, Revilla, Arra C., Herrera, Cheryl, Israel, Mason A., Yuan, Shauna H., Edland, Steven D., Goldstein, Lawrence S.B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388804/
https://ncbi.nlm.nih.gov/pubmed/25772071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.02.004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi