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Loss-of-Function Variants in Schizophrenia Risk and SETD1A as a Candidate Susceptibility Gene

Loss-of-function (LOF) (i.e., nonsense, splice site, and frameshift) variants that lead to disruption of gene function are likely to contribute to the etiology of neuropsychiatric disorders. Here, we perform a systematic investigation of the role of both de novo and inherited LOF variants in schizop...

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Dettagli Bibliografici
Pubblicato in:Neuron
Autori principali: Takata, Atsushi, Xu, Bin, Ionita-Laza, Iuliana, Roos, J. Louw, Gogos, Joseph A., Karayiorgou, Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387883/
https://ncbi.nlm.nih.gov/pubmed/24853937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.04.043
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