ロード中...
Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm
Activation-induced deaminase (AID) initiates mutagenic pathways to diversify the antibody genes during immune responses. The access of AID to the nucleus is limited by CRM1-mediated nuclear export and by an uncharacterized mechanism of cytoplasmic retention. Here, we define a conformational motif in...
保存先:
| 出版年: | J Exp Med |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2015
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387293/ https://ncbi.nlm.nih.gov/pubmed/25824822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141157 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|