Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism

The majority of existing research on the function of metabotropic glutamate (mGlu) receptor 1 focuses on G protein-mediated outcomes. However, similar to other G protein-coupled receptors (GPCR), it is becoming apparent that mGlu(1) receptor signaling is multi-dimensional and does not always involve...

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Vydáno v:Neuropharmacology
Hlavní autoři: Hathaway, Hannah A., Pshenichkin, Sergey, Grajkowska, Ewa, Gelb, Tara, Emery, Andrew C., Wolfe, Barry B., Wroblewski, Jarda T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387075/
https://ncbi.nlm.nih.gov/pubmed/25700650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.02.007
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